Ok so I have Spybot search and destroy and Avast antivirus,

Recently i found was doing a paper (open office, cuz my MS Office 07 trial ran out). And i found that my explorer was acting up. [the task bar] was disappear and reappearing, i attributed it to open office quick start, because as soon as i would close it, the task bar would disappear and reappear. I ran spybot and it found some stuff and i killed it and it seemed to take out that problem, but then i got some confusing reports, there was a registry change (that i had to approve) that i had no idea, no to all of them, i set looked at them and they where all the same, i set it to say no each time. and it just kept going, the same one over and over. at some point the reporter got so filled up it had to quit so i dont know if it allowed it or not. I also uninstalled Open office, so that might be what it was. But it was very strange.